The Surgical Infection Society Europe (SIS-E) Annual Congress, taking place from 16–18 September in the beautiful city of Porto, Portugal. This year’s congress features an innovative and forward-looking scientific programme, showcasing the latest clinical advances in infection prevention, diagnosis, and treatment. Through expert lectures, interactive sessions, debates, and hands-on opportunities, participants will explore emerging challenges and the most up-to-date evidence guiding clinical practice. The programme reflects SIS-E’s ongoing commitment to excellence, scientific rigour, and meaningful real-world impact. SIS-E brings together Europe’s leading experts with a special interest in surgical infections—and distinguished colleagues from around the world—across multiple clinical specialties. Our collective expertise supports the development of high-quality guidelines and drives essential education and awareness initiatives aimed at improving outcomes for patients with infections. The congress provides a unique opportunity to engage directly with these leaders, fostering a rich exchange of ideas and perspectives.