“Responsibility, endurance and resilience” is the motto of the congress. These three key elements guide our daily neurosurgical work, our teaching and our research activities. We witness tremendous technological advances in neurosurgery, such as artificial intelligence, advanced neurostimulation and brain-machine interfaces. We gain new insights from clinical and experimental neuroscience, allowing to approach personalized therapy especially, but not exclusively in neuro-oncology. Nonetheless, a constant awareness of how these advances are responsibly integrated into education and daily practice to truly benefit our patients is needed. In line with the motto of the congress, we aim to provide a comprehensive, educational and also critical update of the most recent developments in neurosurgery, framed by a large exhibition showing the latest technologies.