In this workshop the participants will hear about novel scientific insights into the haematopoietic stem cell niche in normal, clonal and malignant haematopoiesis. The goal of this meeting is to bring together basic and translational scientists, as well as clinicians from all over the world, from academia and industry, with the goal to bring novel niche-targeting approaches into the clinic. The promotion of the scientific interactions between these groups and between junior and more senior scientists and clinicians is another aim of this meeting.